The European Union will ban travellers from outside the bloc for 30 days in an unprecedented move to seal its borders amid the coronavirus crisis.
The measure is expected to apply to 26 EU states as well as Iceland, Liechtenstein, Norway and Switzerland. UK citizens will be unaffected.
The ban came as deaths continued to soar in Italy and Spain, and France began a strict lockdown.
Europe has been badly hit by the virus, which has killed 7,500 globally.
Meanwhile, the Euro 2020 football competition has been postponed by a year.
The virus has infected more than 185,000 people worldwide, according to the World Health Organization.
The travel ban will affect all non-EU nationals from visiting the bloc, except long-term residents, family members of EU nationals and diplomats, cross-border and healthcare workers, and people transporting goods.
Free travel is a cherished principle within the European border-free Schengen area. But in recent days many countries have unilaterally imposed full or partial border shutdowns in a bid to stop the spread of the coronavirus.
The UK and the Republic of Ireland - which is part of the EU but not Schengen - will be invited to join the measure.
In France, citizens who leave home must now carry a document detailing the reasons why, with fines for transgressors to be set at €135.
It comes after President Macron put the country on a war-footing, ordering the population to stay at home and only go out for essential trips.
The number of confirmed cases in France grew by more than 16% on Tuesday, reaching 7,730, The death toll rose to 175, with 7% of the dead aged under 65.
More than 2,500 people are being treated in hospital, including 699 in intensive care.
In Britain, where the death toll is 71, people have been told to avoid social contact, work from home if they can and avoid all non-essential foreign travel.
The chancellor, Rishi Sunak, has unveiled a financial package worth £330bn to ease the burden caused by the virus, after Prime Minister Boris Johnson on Monday urged people to avoid pubs, clubs and cafes.
Meanwhile, the government's chief scientific adviser said it would be a "good outcome" if 20,000 or fewer people died of the virus in the UK.
The latest set of Brexit talks has also been delayed.
The number of confirmed cases in Spain has soared by 2,000 to 11,178. Authorities there are maintaining a partial lockdown on 47 million people.
It is now the European country worst-affected after Italy.
At midnight Spain began stopping cars crossing its borders from France and Portugal. Only Spanish nationals, residents and cross-border workers were being allowed to the country.
Italy, which has registered the most cases outside China at more than 31,500, announced another surge in deaths on Tuesday, from 2,150 to 2,503. The country remains in lockdown.
The government meanwhile is set to renationalise flag carrier airline Alitalia with a rescue package worth $670m.
Germany, which has had more than 6,000 cases and 13 deaths, banned religious services and told people to cancel any domestic or foreign holiday travel.
Venues including clubs, bars, leisure facilities, zoos and playgrounds will be closed. Schools are already shut.
Ireland could have 15,000 cases of coronavirus before the end of March, said PM Leo Varadkar. In a St Patrick's Day address, he warned of "significant and lasting" economic damage, and said the emergency could last into the summer. The government has already closed pubs, schools and universities.
Belgium's death toll doubled from five to 10 on Tuesday
Sweden is to close all high schools and universities from Wednesday
Orthodox priests in Georgia have started blessing the streets of the capital Tbilisi with holy water
Iran remains the world's third-worst-affected nation, after China and Italy.
More than 16,000 people are confirmed as infected and 988 have died.
A spokesman for the judiciary said on Tuesday that 85,000 prisoners, including political prisoners, had been temporarily released to try to combat the spread.
Gholamhossein Esmaili did not say when or how those freed would be returned to prison, but stressed that only prisoners serving five years or less had been released.
Most shops and restaurants remain open but the health ministry has urged people to stay at home.
In the US, the White House is working on an economic stimulus package reported to be worth some $850bn, with Treasury Secretary Steve Mnuchin saying the administration was "looking at sending cheques to Americans immediately".
The total number of cases has risen to above 4,200, with 75 deaths, said the US Centers for Disease Control and Prevention. Most cases are in the states of New York (669), Washington (708) and California (369),
The pandemic has disrupted the Democratic primary election season.
China reported just one new domestic infection on Tuesday - but 20 more from people arriving from abroad.
The Philippines became the first nation to shut its stock exchange indefinitely
Malaysia is barring people crossing the border with Singapore from Wednesday, sparking a rush on food stores in the city state, which depends on Malaysia for supplies
India's iconic Taj Mahal monument has shut down
Scientists in Australia say they have identified how the body's immune system fights the Covid-19 virus